r-interferon alfa-2b/ribavirin combined therapy followed by low-dose r-Interferon alfa-2b in chronic hepatitis C interferon nonresponders
نویسندگان
چکیده
منابع مشابه
Interferon Alfa-2b Therapy in Mucocutaneous Manifestations of Behçet’s Disease
Background: Viral infections such as Epstein-Barr virus and Herpes simplex virus may play a role in the pathogenesis of Behçet’s disease (BD). Interferons (INF) are natural defense mechanisms against viruses and inhibit their activities by enhancing major histocompatibility complex class I and cytokine expression. This study evaluated the efficacy of INF-α-2b on mucocutaneous lesions of BD. Met...
متن کاملTreatment of acute hepatitis C with interferon alfa-2b.
BACKGROUND In people who are infected with the hepatitis C virus (HCV) chronic infection often develops and is difficult to eradicate. We sought to determine whether treatment during the acute phase could prevent the development of chronic infection. METHODS Between 1998 and 2001, we identified 44 patients throughout Germany who had acute hepatitis C. Patients received 5 million U of interfer...
متن کاملResponse to combination therapy of interferon alfa-2b plus ribavirin in Hispanics with chronic hepatitis C.
OBJECTIVE To evaluate the response rate of Hispanics with chronic hepatitis C to combination therapy of interferon alfa-2b plus ribavirin and to assess its adverse events. BACKGROUND Hepatitis C virus may lead to chronic infection and multiple complications. Response to combination therapy of interferon plus ribavirin has been studied in many populations. African Americans have been found to ...
متن کاملLymphoblastoid interferon alfa treatment in chronic hepatitis
Interferon is becoming the standard treatment in adults for chronic hepatitis C. Twenty one children with histologically proved chronic hepatitis C (10 boys, range 2 5-13 years), who were otherwise healthy, were enrolled in a randomised controlled study to test their response to interferon alfa. Eleven children were treated with lymphoblastoid interferon alfa (3 million units/M2) for 12 months;...
متن کاملEffectiveness of interferon alfa-2b/ribavirin combination therapy for chronic hepatitis C in a clinic setting.
AIM To determine effectiveness of treatment for hepatitis C outside clinical trials, by testing the hypothesis that apparent effectiveness and tolerability of interferon alfa-2b/ribavirin combination therapy would be less in a hospital liver clinic setting. DESIGN Retrospective analysis of all patients in one centre commencing interferon alfa-2b/ribavirin therapy, but not in clinical trials, ...
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ژورنال
عنوان ژورنال: Hepatology
سال: 1999
ISSN: 0270-9139,1527-3350
DOI: 10.1002/hep.510290135